Search results for "Type 1 Innate Lymphoid Cells"

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Predominance of Type 1 Innate Lymphoid Cells in the Rectal Mucosa of Patients With Non-Celiac Wheat Sensitivity: Reversal After a Wheat-Free Diet.

2016

OBJECTIVES: Non-celiac wheat sensitivity (NCWS) is defined as a reaction to ingested wheat after exclusion of celiac disease and wheat allergy. As its pathogenesis is incompletely understood, we evaluated the inflammatory response in the rectal mucosa of patients with well-defined NCWS. METHODS: The prospective study included 22 patients with irritable bowel syndrome (IBS)-like clinical presentation, diagnosed with NCWS by double-blind placebo-controlled challenge. Eight IBS patients not improving on wheat-free diet were used as controls. Two weeks after oral challenge was performed with 80 grams of wheat daily, cells were isolated from rectal biopsies and thoroughly characterized by fluore…

wheat-free diet.0301 basic medicineNon-Celiac Wheat SensitivityPathologymedicine.medical_specialtyWheat free dietSettore MED/09 - Medicina Internabusiness.industryOriginal ContributionsInnate lymphoid cellGastroenterologyfood and beveragesType 1 Innate Lymphoid Cell03 medical and health sciences030104 developmental biology0302 clinical medicineRectal mucosaRectal MucosaImmunologyMedicine030211 gastroenterology & hepatologybusinessType 1 Innate Lymphoid Cells; Rectal Mucosa; Non-Celiac Wheat Sensitivity
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